Crews contained a fire at an insulation warehouse in Kearny Mesa on Wednesday afternoon.
Heavy smoke and fire was seen at about 12:40 p.m. Wednesday coming from the one-story building in the 8200 block of Ronson Road, just west of State Route 163.
The area is surrounded by car dealerships.
Crews had to cut down a garage down to enter the warehouse and fight the fire.
The fire destroyed two bays owned by E-Z Flow Foam, a company that sells polyurethane foam and related chemicals.
Crews had the fire contained after 35 minutes.
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No workers were inside when the fire started, but the company's owner is fearful of what's come for his business.
"We have a million-and-a-half-dollar-a-year business here and I don't know what it's going to look like tomorrow," said company owner James Train.
No one was hurt.
Total damage, including the building and its content, was estimated at $275,000. Fire investigators said routine testing of a piece of equipment malfunctioned, triggering the blaze.